Last updated: August 9, 2021

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Welcome to our big anti-wrinkle serum test 2022. Here we present all the anti-wrinkle serums we have tested. We have compiled detailed background information and added a summary of customer reviews on the internet.

We would like to make your purchase decision easier and help you find the best anti-wrinkle serum for you.

You will also find answers to frequently asked questions in our guide. If available, we also offer interesting test videos. Furthermore, you will also find some important information on this page that you should be aware of when buying anti-wrinkle serum.


  • Anti-wrinkle serum is one of the many delivery forms of anti-ageing products, along with creams, gels and concentrates.
  • Many serums contain hyaluron, Q10, vitamins C and E and retinol, which support and increase cell activity.
  • In general, it is said that anti-wrinkle serums should be used from around 30 years of age. It should not be started much earlier, as it may harm the skin.

The Best Anti-Wrinkle Serum: Our Choices

Advice: Questions you should ask yourself before buying anti-wrinkle serum

How does anti-wrinkle serum work?

In general, anti-wrinkle serums make the skin look firmer and fresher and provide a lot of moisture. In addition, these are very complex products that combine different active ingredients and active principles.

Serum is not only available as an anti-ageing product, you can also find many other skin care products in this form. ( / timokefoto)

The vitamin A acid found in most serums targets the cells where collagen is produced and broken down. This helps to stimulate collagen production again. This can prevent the formation of new wrinkles and also reduce existing wrinkles.

In addition, vitamins C and E work against oxidative stress and offer sunlight and smog. In addition, hyaluronic acid, which is present in many serums, helps to retain moisture in the skin. Q10 is also often present in anti-wrinkle serums, which helps regenerate the cells.

When should I start using anti-wrinkle serums?

Generally, it is recommended to start using anti-wrinkle serums at around 30 years of age. Since cellular activity starts to decline at around 25 years of age, many think that you should start using anti-wrinkle serums at that age.

However, you should refrain from using it when you are still young, because using it too early can even damage the skin.

At a young age, you should rather pay attention to a healthy diet, always protect yourself from the sun and do enough sports.

However, if you already want to do something, you can start with an eye cream with either hyaluronic acid or Q10, as these stimulate the regeneration of the cells.

From the age of 30, wrinkles start to become more visible.

Therefore, you can start using anti-wrinkle serums to keep the skin young and fresh. In addition, most products are designed for women over the age of 35.

Since men's cells are still productive longer and cellular activity does not decline until later, it is recommended to start using anti-wrinkle serums from around 35 years of age.

What active ingredients are present in anti-wrinkle serum?

There are many different active ingredients in an anti-wrinkle serum. The most commonly used are vitamins A, C and E, hyaluronic acid and Q10. However, ceramides, glycolic acid and peptides are also often present in these serums.

Vitamin A acid, also called retinol, stimulates the production of collagen and thus strengthens the skin. In addition, vitamins C and E offer protection against UV rays and smog and can alleviate oxidative stress.

Active ingredients such as Q10 and glycolic acid promote the regeneration of the skin and make it look firmer. Glycolic acid also stabilises the pH value of the serum. Peptides are also often present in anti-ageing serums as they give the signal that the repair mechanism needs to be started.

Hyaluronic acid and ceramides are also important active ingredients that help the skin absorb and retain moisture. In this way, they also smooth the skin's structure, making it appear firmer and fresher.

How much does anti-wrinkle serum cost?

The price of an anti-wrinkle serum can vary greatly. The price range of such a serum is between 3 € and 100 €.

Generally, anti-wrinkle serums with hyaluronic acid are more expensive than others. However, other active ingredients can also drive up the price somewhat.

Above all, the brand determines the price of the serum. With higher-quality brands, you can dig a little deeper into your pocket.

Type Price range
Anti-wrinkle serum with hyaluron 5 € - 90 €
Anti-wrinkle serum with Q10 10 € - 70 €
Anti-wrinkle serum with vitamin A, C or E 3 € - 75 €

What are the alternatives to anti-wrinkle serum?

Basically, there are a few alternatives you can use if you don't want to use anti-wrinkle serum. These are mainly other anti-ageing products in the form of creams, gels and concentrates.

However, procedures such as microneedling also help to keep the skin young and firm. Since microneedling also uses various body oils, these can also help against wrinkles.

Alternative Properties
Anti-wrinkle cream Unlike the serum, the cream is not quite as heavily dosed. In addition, this can be used very well as night care, as it is not absorbed as quickly.
Anti-wrinkle gel The gel is similar in consistency to the cream. It also has a cooling effect, which can immediately relieve puffy eyes and a few wrinkles. However, it is not available for every skin type.
Anti-wrinkle concentrate The concentrate is very similar to the anti-wrinkle serum. The only difference is that this is even more concentrated than the serum.
Microneedling Microneedling uses small needles to injure the surface of the skin. This stimulates the skin's own production of collagen and hyaluron, which helps keep the skin firm and smooth.

In addition, it always helps if you eat a healthy diet, drink enough water and protect your skin from the sun.

Decision: What types of anti-wrinkle serum are there and which is the right one for you?

Basically, a distinction is made between two types of anti-wrinkle serum:

  • Anti-wrinkle serum for moisture regulation
  • Anti-wrinkle serum against free radicals

These different types have special properties, which come with individual advantages and disadvantages.

Different variants of anti-wrinkle serum are better suited for special circumstances. The following sections will help you find the right variant.

For this purpose, we will introduce you to the types just mentioned and describe their advantages and disadvantages.

What makes an anti-wrinkle serum moisturising and what are its advantages and disadvantages?

Having enough moisture in the skin helps to counteract skin ageing. As the skin becomes less able to retain and absorb moisture, it is important to choose a serum that supports this function.

  • Moisturises and firms the skin
  • Can be used at any age
  • Skin's own active ingredients
  • Do not protect against free radicals
  • High purchase price

Active ingredients such as hyaluronic acid, lactic acid, urea, panthenol, glycerin and algae extracts help the skin to retain moisture better. This then makes the skin look much fresher and firmer, giving it a younger appearance.

What distinguishes an anti-wrinkle serum against free radicals and what are its advantages and disadvantages?

Exposure to free radicals also contributes to the formation of wrinkles in the skin. Using an anti-wrinkle serum that offers protection against these antioxidants can slow down the skin ageing process.

  • Protects the skin from free radicals and the sun
  • Skin's own active ingredients
  • Firms and smoothes the skin
  • Cannot be used at all ages
  • Does not provide much moisture
  • High purchase price

Active ingredients such as vitamins A, C and E, Q10, flavanoids and polyphenols are particularly helpful. These substances form a light protective film that protects the skin from free radicals, but also UV rays.

However, these active ingredients are somewhat stronger and therefore not yet recommended at a younger age.

Buying criteria: You can use these factors to compare and evaluate anti-wrinkle serums

In the following, we will show you which criteria you should consider and help you decide between the different anti-wrinkle serums.

The factors you can use to compare anti-wrinkle serums include:

  • Skin type
  • Ingredients
  • Area of application
  • Packaging
  • Quantity

In the following sections, we will explain in more detail what is important in each of the criteria.

Skin type

When buying anti-wrinkle serum, it is important to consider your skin type. Different skin types need different care and tolerate different products.

In addition, the serum must be chosen carefully, especially if you have skin diseases, otherwise the symptoms will only be aggravated.

If you know your skin type, you can easily find it on the packaging. If you are not sure, the following video can help you identify your skin type.


To be sure that your anti-wrinkle serum is smoothing, plumping, moisturising and protecting your skin from free radicals, you should pay attention to the ingredients. The different active ingredients care for the skin in different ways.

Generally, the ingredients in serums should be highly concentrated.

This is also stated by the manufacturers. If this is not clear, it indicates that the ingredients are not highly dosed.

In addition, there should not be too many active ingredients in the anti-wrinkle serum, as there is a higher possibility that a bad ingredient is contained.

Area of application

Basically, anti-wrinkle serums are mainly used on the face. However, you should also apply it to the décolleté to ensure a more even result. You should also consider whether the serum should be applied to the whole face or only under the eyes.

If you want to take care of your body, you should rather use moisturisers with Q10. You can also tighten the skin on your body, especially through exercise.


When applying anti-wrinkle serum, you can choose between a pump dispenser or a pipette. It's up to you which one suits you best.

However, pipettes allow you to dose the amount better. On the other hand, with a pump dispenser, the anti-wrinkle serum is not exposed to the air, so it can be better protected from various reactions.


Generally, anti-wrinkle serums are sold in small quantities. However, since not much serum is needed for each individual application, even this small amount is enough for a long time.

Most of the time, you can get anti-wrinkle serum in 30 ml, 50 ml or 60 ml bottles. In addition, the price per 10 ml is usually indicated so that you can better compare the different products.

Facts worth knowing about anti-wrinkle serum

How often should I use anti-wrinkle serum?

For anti-wrinkle serum to be fully effective, you should use it regularly. You should apply it between once a week and every day.

In general, it is important that you do not use the serum too often, otherwise you may get used to it. This means that the skin stops producing important substances even more. If the serum is not a natural product or is very highly concentrated, you should stick to using it once a week.

It also depends on the condition of your skin. You can then increase or decrease the amount of serum you use.

Can I make anti-wrinkle serum myself?

In general, you can easily make anti-wrinkle serum yourself. You can find many different recipes on the internet. However, you sometimes need ingredients that are more difficult to obtain.

Most recipes use a combination of beeswax and various oils. Many recipes are also based on shea butter, argan oil or avocado oil.

For sensitive skin and allergy sufferers, a mixture of hyaluronic acid and aloe vera juice is particularly recommended. Simply mix 0.5 g hyaluronic acid and 50 ml aloe vera juice and you have a nourishing serum. If you like, you can also replace the aloe vera juice with scented water.

How should I apply anti-wrinkle serum?

To support your skin with an anti-wrinkle serum, you only need a small amount of it. All you have to do is put the serum in your hands and then apply it to your face. The serum is also quickly absorbed into the skin.

Nevertheless, you should pay attention to a certain sequence when using it:

  • First, cleanse your face with water and a little toner or lotion.
  • Then massage the anti-wrinkle serum into your face and décolleté.
  • After you have applied the serum, you can continue your day or night care as normal.

If you want to exfoliate, you should also do this before you apply the serum. This way it can be better absorbed into the skin.

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