Last updated: August 11, 2021

Our method

38Products analysed

45Hours spent

44Evaluated articles

168User reviews

Welcome to our big Coenzyme Q10 test 2021. Here we present all the coenzyme Q10 products that we have tested in detail. We have compiled detailed background information and added a summary of customer reviews on the internet.

We would like to make your purchase decision easier and help you find the best coenzyme Q10 supplement for you. You can also find answers to frequently asked questions in our guide. Furthermore, you will also find some important information on this page that you should definitely pay attention to if you want to buy a coenzyme Q10 supplement.




Summary

  • Coenzyme Q10 is an essential component of energy production in the human organism. A Q10 deficiency can have negative effects on your body.
  • It can be produced by the organism itself. In addition, it can be supplied with food or through dietary supplements.
  • The most important effects of Q10 are its antioxidant and immune system-boosting effects and improved energy production.

The Best Coenzyme Q10: Our Picks

Guide: Questions you should ask yourself before buying coenzyme Q10

What is coenzyme Q10?

Coenzyme Q10, or Q10 for short, is a substance produced naturally in the body. It has a great importance in the human body and is essential for energy production. Q10 can basically be produced by the body itself. In addition, our liver has the ability to produce high-quality Q10 from animal and plant food that we eat every day.

Therefore, our body automatically ensures that we are well supplied with it. In order for us to remain healthy and efficient, it is important that our body is sufficiently supplied with Q10.

It is present in every cell in the human organism and is not called an "all-round talent" without reason.

The coenzyme Q10 is important for us to remain fully healthy and efficient. Q10 plays an indispensable role in energy production in the body. (Image source: pixabay.com / sasint)

What effect does coenzyme Q10 have in the body?

Coenzyme Q10 has a variety of health-promoting effects in our body. We explain the most significant effects of Q10 and how they appear in you here.

Improving energy production

Q10 plays an important role in energy production in the mitochondria of the body's cells. Mitochondria can be seen as the power plant of the cell. They provide the necessary energy production and communication in and between the cells.

So what does the coenzyme have to do with this? Q10 starts the whole process. So without Q10 there is no energy. The coenzyme makes sure you stay focused. It also improves physical performance during exercise, according to a study by the Department of Physiology at Osaka City University.

Strengthening immune function

Q10 acts as an immune regulator and immune function booster in the human body. The immune system ensures that we are not weakened by harmful viruses and bacteria from outside and remain healthy.

A study by the Institute for Biomedical Research proves that the number of antibodies is increased by the coenzyme.

Antioxidant effect

When energy is produced, harmful compounds are formed. These are called free radicals and damage our cells. Coenzyme Q10 tries to counteract this cell-damaging process. Q10 is in fact an antioxidant and catches the free radicals and prevents this damage.

For whom is coenzyme Q10 suitable as a supplement?

Basically, our body is a very good producer of coenzyme Q10. This means it produces enough of it and thus takes care of our health. In some cases, however, it may be advisable to take Q10 regularly.

The production of Q10 in the organism decreases with age. Therefore, taking a supplement is recommended from the age of 30 or at the latest from the age of 40.

Furthermore, non-health-promoting factors can cause a deficiency. These include excessive consumption of alcohol and cigarettes. An unbalanced diet and too much or too little exercise are responsible for insufficient saturation of Q10 in the body.

Our research has shown that coenzyme Q10 has a preventive or regulating effect on the following diseases:

  • Obesity
  • Alzheimer's
  • Burnourt
  • Diabets (1)
  • Inflammations
  • Fertility disorders
  • Cardiovascular diseases (2, 3)
  • Migraine (4)
  • Nervous insufficiency

If the above factors apply to you, it is recommended to take coenzyme Q10. Do you simply want to do something good for your body? Do you want to increase your energy level and ability to concentrate? Then there is nothing to be said against supplementing with Q10.

How should I take coenzyme Q10?

It is advisable to take coenzyme Q10 if a deficiency has been diagnosed by a doctor. Ideally, the doctor will recommend the dosage and duration of intake.

Basically, a daily intake of 10 to a maximum of 30 mg per day is recommended. You should take this during a meal.

The effect is best in combination with food. There is very little danger of overdosing, as Q10 that is not needed is simply excreted again.

If you are trying to alleviate one of the diseases mentioned, it is recommended to take at least 100 mg daily. Depending on the severity, the dose is between 100 and 500 mg.

How much does coenzyme Q10 cost?

The average cost of coenzyme Q10 is between EUR 20 and EUR 120 per 100 g. Depending on the package contents, dosage, ingredients, etc., the prices vary.

The best way to find the best product for you is to compare the products based on the factors listed in the chapter on buying criteria.

What alternatives are there to coenzyme Q10?

Since Q10 is a coenzyme and is therefore also taken as a supplement, there is no alternative in this sense. However, coenzyme Q10 has a similar chemical structure as vitamin E and vitamin K.

To strengthen the effect of Q10, you can therefore take the coenzyme together with vitamin E. Here I would like to introduce you to some foods that you can eat instead of the coenzyme to increase your Q10 levels:

Food Coenzyme Q10 content - per 100 g
Sardines 6.4 mg
Beef 3.3 mg
Pork 3.2 mg
Olive oil 3.0 mg
Cheese general max. 0.4 mg
Broccoli 0.86 mg
Spinach 0.36 mg
Peppers 0.33 mg
Lettuce 0.22 mg

Decision: What types of coenzyme Q10 are there and which is right for you?

Do you want to include Q10 in your diet? Then it is first important to know the difference between the two types of Q10. Basically, you can distinguish between two types of coenzyme Q10:

  • Q10 Ubiquinol
  • Q10 ubiquinone

Depending on your reasons for wanting to take Q10, a certain Q10 is best suited for you. It is important that you first familiarise yourself with both types in order to make the right decision.

Each form has different advantages and disadvantages. We will explain these two types of coenzyme Q10 in the next section. This should help you find the right coenzyme for you. Below you will find a detailed explanation and the advantages and disadvantages of using each type.

Q10 ubiquinone occurs naturally in food. The daily requirement can be well covered by a varied diet. (Image source: pixabay.com / dbreen)

What distinguishes coenzyme Q10 ubiquinol and what are its advantages and disadvantages?

Coenzyme Q10 ubiquinol is also called the active form of Q10. It does not have to be converted by the body in order to have an effect. This type of Q10 has only been available as a food supplement since 2006. This is because a method had to be found first to stabilise ubiquinone.

Ubiquinol is milky-white in colour. This form of the coenzyme is chemically less stable than ubiquinone. In addition, it oxidises more quickly when it comes into contact with oxygen. Taking ubiquinol is recommended if a Q10 deficiency has been diagnosed.

It has a high bioavailability and gets directly into the pathways of our organism. High bioavailability means that a large proportion of the active ingredient can be used unchanged by our body.

Since Q10 Ubiquinol can be used in a very high quality, it is important to pay good attention to the dosage in this case. Compared to Q10 ubiquinone, our body needs smaller doses of it.

Advantages
  • High biodiversity
  • Lower dose necessary
Disadvantages
  • Oxidises faster
  • More difficult dosage

What distinguishes coenzyme Q10 ubiquinone and what are its advantages and disadvantages?

Coenzyme Q10 ubiquinone is also known as normal Q10. It is found in many foods. Therefore, this type of Q10 can be easily absorbed into the body through food. Since this form of Q10 has been known since 1957, it is also contained in most conventional food supplements.

Its chemical compound is very stable compared to ubiquinol. Ubiquinone is orange-yellow and oxidises less quickly. After oral intake, ubiquinone must first be converted into ubiquinol in order to trigger the desired effect. In this process, the substance is absorbed by the enterocytes of the small intestine wall and then converted into the active form. Therefore, ubiquinone also has a lower bioavailability.

The positive effects on the body remain. With increasing age, our organism can no longer convert ubiquinone into its active form as quickly and easily as this type of Q10.

Advantages
  • Large supply on the market
  • Can be absorbed with food
  • Contained in numerous foods
Disadvantages
  • Low bioavailability
  • Conversion to ubiquinone necessary
  • Higher dose necessary with increasing age

Buying criteria: Use these factors to compare and evaluate coenzyme Q10

In the following we would like to show you which factors you can use to decide between the different Q10 products. These aspects will make it easier for you to compare and evaluate the different preparations. We hope that this will make it easier for you to find the right product for you. You can use these points to compare and evaluate the Q10 products:

  • Type of Q10
  • Form of intake
  • Variety of contents
  • Dosage
  • Type of fermentation

In the next section, you can learn more about the individual criteria and use them to make your decision.

Type of Q10

As already explained in detail, you will find Q10 on the market both active, as ubiquinol, and normal, as ubiquinone.

Our body's ability to convert ubiquinone into ubiquinol decreases over time.

It is advisable to turn to ubiquinol as we age. In younger years, the normal form, i.e. ubiquinone, can be taken without any problems.

Form of intake

You can take Q10 in the form of capsules or apply it to the skin in the form of a cream. Q10 is taken orally, i.e. by mouth, in the form of capsules. The capsules are available in different dosages. Some suppliers have special offers with additional ingredients. These can be supplemented with zinc, for example.

Q10 is available on the market in the form of capsules. This form has the great advantage that the capsules can be dosed easily and precisely. (Image source: pixabay.com / eliasfalla)

It should be noted that conventional capsules are of animal origin. They are made from gelatine. If you do not want to take such capsules, there are also suppliers who produce Q10 capsules with both vegetarian and vegan raw materials.

In the anti-ageing industry, creams have been enriched with Q10 for a long time. The ingredient helps to smooth skin with cellulite and wrinkles. It also protects the cells from free radicals and oxidative stress. Here you can find the most important points in a table:

form of intake Good-to-Know
capsules intake with water, exact dosage, practical for on the go, regular intake
cream application via application to the skin, additional active ingredients in the cream, application in anti-aging

Variety of content

Coenzyme Q10 is offered in the form of capsules in different package sizes and with different capsule contents. The dose of Q10 in the capsules varies greatly.

There are suppliers who offer a Q10 dose of 10 mg per capsule and others with 700 mg per capsule. Therefore, always check the contents on the back of the package first. Here you should decide for yourself whether you want to take 100 percent Q10 or not.

Combination preparations such as Q10 with vitamin E are very popular because of the supplementary effect. Capsules with a high proportion of Q10 are often developed to strengthen the immune system. These then contain a wide variety of other vitamins to boost your immune system.

Dosage

The daily dose of Q10 depends entirely on your situation and the goal you want to achieve. The daily intake should therefore be adjusted to your actual needs. A normal adult should have 0.85 µg/ml of coenzyme Q10 in their blood plasma.

This corresponds to a daily dose of about 50 mg Q10 ubiquinol. This value is recommended for a normal-weight adult. The daily requirement increases to about 2.5 µg/ml in case of illness. Depending on the disease or therapy, the dose can be between 100 and 500 mg per day.

In this case, it is recommended to consult a doctor. An overdose is only harmful in very few cases. Our body breaks down excess Q10 or converts it into ubiquinone. Symptoms of an overdose are abdominal pain, indigestion and cold symptoms.

Type of fermentation

Q10 can be produced industrially either by fermentation of yeasts and bacteria or by chemical synthesis. Ubiquinone is produced during yeast fermentation. The safety of the intake and tolerability was proven in a placebo-controlled study.

Q10, which is produced by chemical synthesis, has not yet been tested for its 100 percent safety. Therefore, it is recommended to pay attention to the production method before buying.

Facts worth knowing about coenzyme Q10

What are the side effects of coenzyme Q10?

Our body simply excretes excess coenzyme Q10 when it is not needed. It also converts it into its inactive form, which is not yet effective as ubiquinone. However, an overdose can lead to the following side effects in certain cases:

  • Diarrhoea
  • Nausea
  • Loss of appetite
  • Malaise
  • Symptoms of an incipient cold

Side effects, however, occur only very rarely. Moreover, these are only observable with an overdose of 50 to 300 mg per day.

The negative interaction with blood coagulation inhibitors (vitamin K antagonists) can be a cause for concern.

Does coenzyme Q10 promote the likelihood of becoming pregnant?

As soon as an egg cell is on its way to ovulation, it needs a large amount of coenzyme Q10. Without the coenzyme there would be no ovulation. An increased supply of Q1 can therefore lead to an improvement in egg quality. However, there is no guarantee of this.

How does a deficiency of Q10 affect the body?

As already explained, the coenzyme Q10 is essential for the body's energy production. The mitochondria are significantly involved in this. A Q10 deficiency of at least 25 % already causes damage to the mitochondria. This enormous loss of energy can have harmful effects on all processes in the human organism.

Image source: pexels.com / Nathan Cowley

References (4)

1. Hodgson JM, Watts GF, Playford DA, Burke V, Croft KD. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr. 2002 Nov;56(11):1137-42.
Source

2. A Domnica Fotino, Angela M Thompson-Paul, Lydia A Bazzano. Effect of coenzyme Q10 supplementation on heart failure: a meta-analysis. The American Journal of Clinical Nutrition. February 2013; Volume 97, Issue 2, Pages 268–275.
Source

3. Werner Goller. "Was verschweigt die Schulmedizin?" 2009; S. 26

4. Hershey AD, Powers SW, Vockell AL, Lecates SL et al. Coenzyme Q10 deficiency and response to supplementation in pediatric and adolescent migraine. Headache. 2007 Jan;47(1):73-80.
Source

Why you can trust me?

Wissenschaftliche Studie
Hodgson JM, Watts GF, Playford DA, Burke V, Croft KD. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr. 2002 Nov;56(11):1137-42.
Go to source
Wissenschaftliche Studie
A Domnica Fotino, Angela M Thompson-Paul, Lydia A Bazzano. Effect of coenzyme Q10 supplementation on heart failure: a meta-analysis. The American Journal of Clinical Nutrition. February 2013; Volume 97, Issue 2, Pages 268–275.
Go to source
Wissenschaftlicher Artikel
Werner Goller. "Was verschweigt die Schulmedizin?" 2009; S. 26
Wissenschaftliche Studie
Hershey AD, Powers SW, Vockell AL, Lecates SL et al. Coenzyme Q10 deficiency and response to supplementation in pediatric and adolescent migraine. Headache. 2007 Jan;47(1):73-80.
Go to source
Reviews