Last updated: August 12, 2021

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Welcome to ReviewBox Brasil. Today we are going to talk about glucosamine, an indispensable supplement for the formation, lubrication, preservation and restoration of the joints.

The supplement can be consumed by men and women of all ages, both by those who have pre-disposition or problems with the joints, and by those who practice high intensity physical exercise.

But before including glucosamine in your routine, you need to know all the benefits of the supplement and how to take it correctly. You will find this and other information in this article.


  • Glucosamine has the function of preserving and restoring the joints. Continuous use of the supplement prevents and treats injuries, combats pain and improves quality of life.
  • The glucosamine supplement may have other components such as chondroitin, MSM, collagen and hyaluronic acid. The product is sold as tablets, capsules or powder.
  • When used by athletes and sportspeople, glucosamine provides strength, flexibility, mobility and comfort to exercise. The supplement also relieves stress caused by physical activity.

The Best Glucosamine: Our Picks

Buying Guide

What is glucosamine used for? What are the benefits of this supplement? What is the recommended daily dose? Do I need a prescription to buy it? Does it have any side effects? Where can I find it? How much does it cost?

In this Buying Guide we will answer these and other questions and talk about all the benefits of glucosamine for the health of your joints. Enjoy your reading!

Imagem de um casal caminhando.

The glucosamine supplement preserves the integrity of the joints. (Source: Pexels / Pixabay)

What is glucosamine?

Glucosamine is a substance produced naturally by the body through the union of glucose and glutamine. The functions of glucosamine encompass the formation, maintenance and preservation of the cartilage present in the joints.

The problem is that the natural production of glucosamine is insufficient to meet the needs. And with physical effort and over the years, the amount of glucosamine in the body decreases even more.

The absence of glucosamine generates discomfort, pain, stiffness and joint diseases.

In this case, the recommendation is to include a glucosamine supplementation. The supplement is the best alternative to ingest the necessary amount of the substance, preserve the health and integrity of the joints.

Generally, the supplement is produced by extracting glucosamine from crustaceans, but nowadays you can find options produced through vegetable sources, an excellent alternative for vegans and vegetarians.

Imagem de uma jovem alongando.

Glucosamine supplementation is beneficial for men and women of all ages. (Source: Nathan Cowley / Pexels)

What are the benefits of glucosamine?

Glucosamine has numerous benefits for men and women of all ages. The most interesting thing is that the supplement brings results in the short, medium and long term.

Prevention and treatment of joint diseases

Before we talk about the prevention and treatment of joint diseases, it is important to explain what joints and articulations are. Joints are the areas where two or more bones come together.

Joints can be fixed, such as those in the skull, or have mobility, which allows people to be able to perform various movements, these are called joints.

The primary function of glucosamine is to keep joints healthy and intact. But the supplement is also effective in preventing joint injuries or joint aggravation.

Imagem de uma pessoa tendo o joelho examinado por um ortopedista.

In the short term, glucosamine supplementation treats pain caused by joint injuries. (Source: whitesession / Pixabay)

For people with genetic pre-disposition to joint diseases such as arthritis, arthrosis and rheumatism, the supplement inhibits enzymes that are responsible for cartilage degradation.

Glucosamine also helps prevent the deterioration of type II collagen, an essential protein for joint health. Another benefit is the retention of synovial fluid, essential in the lubrication of the joints.

For people who already have joint diseases, the supplement is the only way to restore glucosamine levels quickly. But it is important that the supplement is indicated for this purpose.

The supplement will reduce pain in the joints.

The supplement will reduce the inflammatory process, reduce discomfort and pain in the joints. Other advantages are: increase in cartilage synthesis and gain of mobility in the joints.

In addition, the supplement attenuates accelerated joint degradation, preventing/delaying the degenerative process. Another benefit is that glucosamine acts in cartilage regeneration.

Glucosamine also relieves inflammation of the vertebral discs, reducing back pain, helps fight inflammation and pain in the sciatic nerve (main nerve of the lower limbs).

Imagem de uma mulher massageando a coluna de um homem.

Glucosamine also decreases back pain. (Source: whitesession / Pixabay)

Benefits for people who practice physical activity

One of the groups that are most susceptible to suffering from joint problems are athletes. And most of the injuries suffered in sports are related to excessive physical activity.

Most people acquire injuries in the legs, feet and ankles, which are the areas most susceptible to the impacts caused by exercise. Generally, these injuries are caused by a lack of balance between post-workout recovery time and the execution of a new series of exercises.

Imagem de uma pessoa massageando os pés de outra.

The feet and ankles region is one of the most affected by joint injuries acquired during physical exercise. (Source: andreas160578 / Pixabay)

It is important to note that joint injuries will accumulate and increase over time, causing discomfort, stiffness and pain in the affected areas.

Therefore, for people who practice physical exercises of high impact and intensity, the supplement is indispensable, after all, one of the causes of deficiency of this substance is physical wear.

With regular use of the supplement, you will acquire strength, flexibility, mobility and range of movement. In this way, you will be protecting your joints from degenerative lesions resulting from poorly executed exercises.

Imagem de uma mulher correndo.

Glucosamine lubricates, hydrates, nourishes and protects your joints. (Source: Pixabay / Pexels)

What other benefits does glucosamine have?

Glucosamine has other benefits in addition to those mentioned above. One of them, is that the substance contributes to the proper functioning of the circulatory and digestive systems.

The supplement also increases the rates of glutathione in the body, a substance known for its antioxidant property that fights molecules that damage and age the cells.

Glucosamine also has aesthetic benefits, as it helps maintain younger-looking skin. The substance provides support, elasticity and hydration to the skin of the body and face.

  • It serves to prevent, treat and repair injuries in the joints
  • It can be enriched with other components such as chondroitin, MSM, collagen and hyaluronic acid
  • The supplement can be in capsules, tablets or powder
  • It can be used by sportsmen, athletes and people with pre-disposition to joint problems
  • It is an expensive supplement
  • It can increase the levels of glucose in the blood
  • It is not indicated for people with allergies to seafood
  • Few options of national origin

Who can take glucosamine?

The glucosamine supplement is indicated for athletes, sportspeople, the elderly and people with joint problems due to physical exercise or genetic predisposition.

But before enjoying the benefits of the glucosamine supplement, it is important to consult a doctor so that the professional can establish the dose and duration of the treatment according to your needs.

To take full advantage of the benefits of glucosamine it is important to maintain an adequate diet, rich in antioxidants and proteins. Other tips are to maintain good posture and to exercise properly

What is the recommended daily dose of glucosamine?

The recommended daily dose of glucosamine is 1500 mg, enough to preserve joint health, reduce pain caused by joint injuries and promote mobility.

You can either take the supplement first thing in the morning in one sitting or split the dose into two portions. If taken in the recommended dose, the supplement has no side effects.

Imagem das mãos de um idoso separando comprimidos.

Elderly people also benefit from the effects of glucosamine. (Source: budabar / 123rf)

Can everyone take glucosamine?

Not everyone can take glucosamine. This is the case for pregnant women and children. People with diabetes should be somewhat careful, as glucosamine can increase blood sugar levels.

If you are allergic to seafood avoid taking glucosamine from animal sources, as the supplement is extracted from the exoskeleton of shellfish. In this case, look for a supplement of plant origin.

What are chondroitin and MSM?

Most glucosamine supplements have two other substances in the composition: chondroitin and MSM. We will talk about the characteristics and benefits of these substances throughout this section.

Chondroitin is produced naturally by our body. This substance surrounds the cells and allows the transport of essential elements in the functioning of the organism.

Did you know that chondroitin is also present in cartilage and is part of the composition of the synovial fluid in joints, essential for smooth and painless joint movements

The substance also has anti-inflammatory properties, delays joint wear and tear and has the capacity to retain water in cartilage, strengthening it and increasing its resistance.

Chondroitin supplementation is necessary when there is an imbalance between catabolism (breakdown of cells) and anabolism (production of cells). This happens when the cartilages present in the articulations are worn out or destroyed.

MSM (methylsulfonylmethane) is a natural sulphur compound that brings numerous benefits, such as good functioning of the joints (prevents injuries), anti-inflammatory action (treats injuries) and relief of discomfort and pain.

Other benefits are:

  • Hydrates the skin
  • Strengthens the nails
  • Reduces muscular pain
  • Reduces post-workout muscle recovery time
  • Has antioxidant action
  • Protects the organism against autoimmune diseases

How much does glucosamine cost?

Glucosamine is priced higher than most products in this category. You can find options starting at £ 65, but most supplements cost over £ 100. The most expensive ones cost up to £ 350.

Purchase Criteria: Factors to Compare Glucosamine Models

After learning about the benefits of Glucosamine, you must be excited to include the supplement in your daily life. But before you buy the product, check out some tips we've separated to help you choose the ideal supplement:

  • Presentation
  • Extra substances
  • Concentration
  • Origin

We will explain each of the items throughout this section


Glucosamine is available in different presentations: capsules, tablets or powder. The supplement in sachets is cost-effective as one packet provides the required amount of supplement.

If you buy the supplement in capsules, it is important to observe the ratio between the recommended dose and the number of capsules per bottle, as consumption varies from one to four capsules per serving.

Extra substances

Glucosamine supplements usually contain additional ingredients. The main ones are chondroitin and MSM, but you can also find products enriched with collagen and hyaluronic acid.

Chondroitin strengthens cartilage, increases resistance to compression, stimulates synovial fluid (to lubricate the joints), increases cushioning capacity and improves anabolism.

Hyaluronic acid also aids joint lubrication by acting as joint fluid. In this way, joint movement becomes smoother and painless.

Imagem de uma mulher fazendo pilates.

Glucosamine increases the mobility of the joints. (Source: lograstudio / Pixabay)

Collagen is a protein that makes up the body's tissues. It is present in the skin, hair, nails and the joints. MSM is essential for collagen synthesis.


If you buy a glucosamine supplement with other components, be aware of the concentration of each in the formula:

  • Glucosamine: 1500 mg
  • Chondroitin: 200 to 1200 mg
  • MSM: 1000 or 1500 mg
  • Hyaluronic Acid: 3 to 30 mg
  • Collagen: 300 mg


You will find it somewhat difficult to find glucosamine supplements manufactured domestically.

The good news is that imported supplements are very good because there is a long history of research to develop the product and strict quality control in production.

(Source of the highlighted image: Stevepb / Pixabay)