Are you overweight and neither exercise nor a strict diet can help you lose weight? Then the dietary supplement phentramine could be an option for you. In our phentramine test 2022 we present phentramine, its mode of action and its side effects clearly based on scientific studies.
This way you can form your own opinion about phentramine. We also tell you how to take phentramine, where you can buy it, who phentramine is not suitable for and what alternatives there are.
- 1 Weekly newsletter with the best personal finance tips
- 2 Summary
- 3 The Best Phentramine: Our Picks
- 4 Buying and evaluation criteria for phentramine
- 5 Guide: Frequently asked questions about phentramine answered in detail
- 5.1 What is phentramine?
- 5.2 How does phentramine work?
- 5.3 When and for whom is it useful to take phentramine?
- 5.4 How should I take phentermine?
- 5.5 What types of phentermine are available?
- 5.6 What are the side effects of taking phentramine?
- 5.7 Who should not take phentramine?
- 5.8 What alternatives are there to phentramine?
- Phentramine is a prescription drug that is taken over a short period of time to lose weight. Phentramine has not been available in Germany since the 1970s.
- Phentramine is prescribed to people with a BMI (body mass index) of 30 who do not lose weight despite an active lifestyle and a calorie-reduced diet.
- Phentramine is available in capsule and tablet form. Side effects can include dry mouth, constipation, insomnia, nervousness, cardiovascular disorders and high blood pressure.
The Best Phentramine: Our Picks
Buying and evaluation criteria for phentramine
Phentramine products differ with regard to the following properties:
In the following, we go into more detail about the individual purchase and evaluation criteria and tell you what you should look out for when taking phentramine.
Phentramine is available both as a tablet and as a capsule. Both dosage forms have their advantages and disadvantages.
If you don't like taking tablets, you should take capsules. The coating makes them easier to swallow. The capsule also protects the active ingredient from stomach acid, so it can fully develop.
If you have no problem taking tablets, you can opt for this cheaper alternative. However, phentramine in tablet form can still affect your digestive tract.
Phentramine is available in the following dosages: 8 mg, 15 mg, 30 mg, 37.5 mg.
Your doctor must determine the correct dosage. You should stick to this dosage and neither exceed nor fall below it. This is the only way to achieve the desired effect.
Stronger doses of phentramine (15-37.5 mg) should be taken once a day 1 hour before breakfast. Alternatively, you can take them 1-2 hours after breakfast. Lower doses (8 mg) are usually taken three times a day 30 minutes before a meal.
Pure phentramine products are rather rare, as humans have built up a tolerance to the substance after about 12 weeks. Therefore, other ingredients are added to prolong or enhance the effect. The following substances may be included:
You should check the ingredients carefully. You should be able to tolerate these.
Guide: Frequently asked questions about phentramine answered in detail
In order to provide you with sufficient information about phentramine and its mode of action, we have compiled the most important information, including scientific studies, in the following paragraphs.
What is phentramine?
Phentramine is a prescription drug in the USA. In Germany, phentramine has not been approved since the 1970s because it has had a negative effect on heart valves. Since 2012, phentramine has been used in the USA in combination with topiramate as an appetite suppressant for the treatment of obesity. This is also not permitted in Germany because the risk of this drug is estimated to be higher than its benefit (1).
Phentramine falls under the category of stimulants. A stimulant improves or increases nerve function. Phentramine is more precisely an amphetamine-like substance. It has a very invigorating and euphoric effect and stimulates the nervous system. Pure phentramine products are rare. Often, several active substances are combined to achieve better results.
The table gives you an overview of the substances that can be contained.
|Active ingredient||Mode of action|
|Caffeine||Caffeine is probably the best-known stimulant. It can invigorate the body, improve the function of the nervous system and suppress the feeling of hunger for a short time. It can also improve fat breakdown, meaning more fat is burned (3).|
|Tyrosine||Tyrosine is an amino acid that positively influences the production of dopamine. Dopamine is often referred to as the "happy hormone". Tyrosine can reduce stress and increase well-being. If you suffer from concentration problems during your diet, tyrosine can help you (4, 5, 6).|
|Naringin||Naringin is a bitter substance that can reduce appetite. Furthermore, naringin increases the potency of stimulants. This means that the body burns more calories (7).|
|Tryptophan||Tryptophan is an amino acid that increases serotonin levels. This reduces stress and lifts your mood. It can also have a positive effect on your sleep and inner peace (8).|
You cannot get pure phentramine from certain foods, unlike some of the substances listed above that may be present in phentramine products. Phentramine intake must be obtained by taking phentramine products.
How does phentramine work?
- stimulates fat burning
- appetite suppressing
- Counteracting secondary diseases
In the following, we explain the effects in more detail based on studies.
Phentramine can have a weight-reducing effect. A study from Korea shows that taking pure phentramine can lead to weight loss and a smaller waist circumference in overweight patients (9).
Other studies investigated the effect of phentramine in combination with topiramate. The results confirmed that this drug can reduce body weight in overweight adults. Long-term studies are desired, as side effects may occur (1, 10).
Increased fat burning
Phentramine can increase fat burning and thus lead to faster weight loss. The Korean study proves this. Subjects treated with phentramine achieved greater success in losing weight than the placebo group (9).
The feeling of hunger can be a big problem when losing weight. Studies have shown that phentramine can suppress the feeling of hunger. Patient groups treated with phentramine clearly feel less hunger than the placebo groups (9, 11).
Counteracts secondary diseases
Common secondary diseases of obesity can be high blood pressure, high cholesterol or diabetes. Studies show that phentramine can also have a positive effect on these conditions. Systolic blood pressure as well as cholesterol-triglyceride and glucose levels could be lowered.
It can therefore be concluded that phentramine, in addition to its weight-reducing effects, can also lower blood pressure and cholesterol levels and reduce the risk of developing diabetes (1, 2). However, another study has shown that sympathomimetics, of which phentramine is one, can increase blood pressure (12).
When and for whom is it useful to take phentramine?
Phentramine is mainly prescribed to overweight people with a BMI of 30 or more. In some cases, people with a BMI of 27 are treated with phentramine if they suffer from obesity-related diseases. These include high blood pressure, diabetes and high cholesterol.
However, phentramine alone is not enough to reduce your weight. During your treatment with phentramine, you still need to exercise a lot and watch what you eat. Taking phentramine is not a substitute for exercise or diet.
How should I take phentermine?
Basically, you should take phentramine (15-37.5 mg) once a day before breakfast. This way, the feeling of hunger is curbed immediately and an appetite-suppressing result can be achieved, as you already eat less at breakfast. With lower-dose products (8 mg), phentramine can be taken three times a day 30 minutes before a meal.
Phentramine should be taken for a maximum of 12 weeks. The effect wears off over time because people build up a tolerance to the substance. Phentramine in combination with other ingredients can be taken for longer. The additional substances can enhance and prolong the effect.
What types of phentermine are available?
Phentramine in capsule form is easier to dose and more pleasant to swallow because of its smooth surface. In addition, the capsule serves as protection against stomach acid and unpleasant tastes. Thus, the active ingredient is better protected and the digestive tract is not affected.
Phentramine in capsule form is the higher quality version and therefore more expensive. However, if you want the best possible results, we recommend capsules made from cellulose or gelatine.
Phentramine in tablet form is the cheaper alternative. This is because it is easy to produce. The substance is available in powder form and is pressed with other excipients into a tablet without coating.
Disadvantages may be that the excipients can negatively affect the digestive tract. In addition, people may find it difficult to swallow the rough tablets without a coating.
What are the side effects of taking phentramine?
- Dry mouth
- Cardiovascular disorders
- High blood pressure
- Paraesthesia (abnormal body sensation)
- Taste disorders (1, 9, 10, 12)
Higher dosages are more likely to cause depression or anxiety disorders. This suggests that lower dosages are better tolerated (10).
Who should not take phentramine?
Therefore, people with high blood pressure should not be treated with phentramine.
Furthermore, phentramine is not suitable for pregnant women, people with cardiovascular diseases and a history of drug abuse (13). Children should also not take phentramine.
What alternatives are there to phentramine?
|Alternative||Mode of action|
|Green tea||Green tea boosts fat burning and is therefore a good aid to losing weight. In addition, the bitter substances curb cravings (14). Instead of drinking green tea, you can also take the extract in capsule form.|
|Green coffee beans||Green coffee beans are unroasted coffee beans. The extract is also available in capsules. It can help with weight loss by reducing body fat (15).|
It is best to consult your doctor. He or she can help you decide between the active ingredients.
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Siebenhofer A, Jeitler K, Horvath K, et al. Long-term effects of weight-reducing drugs in people with hypertension. Cochrane Database Syst Rev. 2016;3:CD007654. Published 2016 Mar 2. doi:10.1002/14651858.CD007654.pub4
Chukir T, Shukla AP, Saunders KH, Aronne LJ. Pharmacotherapy for obesity in individuals with type 2 diabetes. Expert Opin Pharmacother. 2018;19(3):223-231. doi:10.1080/14656566.2018.1428558
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Bong-Keun Choi, Sung-Bum Park, Dong-Ryung Lee, Hae Jin Lee, Ying-Yu Jin, Seung Hwan Yang, Joo-Won Suh. Green coffee bean extract improves obesity by decreasing body fat in high-fat diet-induced obese mice. Asian Pacific Journal of Tropical Medicin. 2016;9:7, 635-643. https://doi.org/10.1016/j.apjtm.2016.05.017