Last updated: August 10, 2021

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Are you looking for information about sulforaphane? Do you want to know how it works and what it can help you with? Maybe you are not yet completely convinced of its effectiveness and want to consolidate your knowledge a little? Then this is the right test for you.

Within the framework of this Sulforaphane test 2021, we want to provide you with all the necessary information so that you are well advised before and after the purchase. You will learn a lot about the mode of action and one or two new things about sulforaphane itself.




The most important facts

  • Sulforaphane is a natural active ingredient found in cruciferous vegetables and is known as a secondary plant substance.
  • The active ingredient has some positive effects, so it is mainly used in the treatment of cancer, asthma or intestinal diseases. It can also have positive effects on children.
  • The highest concentration is found in broccoli or broccoli sprouts. Sulforaphane can be taken and used without hesitation.

The Best Sulforaphane: Our Picks

Guide: Questions you should ask yourself before buying sulforaphane

What is sulforaphane?

Sulforaphane is a mustard oil that is extracted from glucoraphanin in an enzymatic process. This ingredient is found mainly in cruciferous vegetables. (1) These plants include various types of cabbage, cress, radish and many more.

Sulforaphan-1

The classic vegetable for sulforaphane is broccoli.
(Image source: 123.com / The classic vegetable for sulforaphane is broccoli.
(Image source: 123rf.com / Hofacker)

Sulforaphane is a secondary plant substance, which means that it is neither essential for humans nor for the plant itself. However, these substances usually have a positive effect on the metabolism.

How does sulforaphane work?

Sulforaphane is a strong antioxidant. These substances fight free radicals in your body, which can be destructive if too many are present. These free radicals accelerate ageing and weaken the immune system, which can be counteracted with the help of various antioxidants.

An additional difference to vitamin C or E is the way it works. Sulforaphane acts from the background and uses the body's own enzymes for detoxification. This is referred to in technical language as the so-called phase II detoxification enzymes. (2)

For whom is sulforaphane useful?

The field of application of sulforaphane and other secondary plant substances is relatively broad. On the one hand, sulforaphane can be used for prevention and on the other hand, it is increasingly used for the treatment of various diseases.

Among other things, it is used for

  • Asthma (3)
  • Hay fever
  • Arthrosis (4)
  • Intestinal diseases
  • Cancer (5, 6)

This substance, which has only been known since 1992, is being researched and tested in ever greater depth. This means that the area of application is developing further and further.

What does sulforaphane cost?

Depending on the form of sulforaphane, it costs different amounts. The capsules are usually a little more expensive than the powder. You can get the cheaper price by buying broccoli, but the dosage is a little more difficult.

Form Price
Powder 20 to 30 euros
Capsules 45 to 60 euros

What side effects can occur with sulforaphane?

At the moment, no side effects are known to occur due to an above-average intake of sulforaphane.

One side effect of an increased intake of cabbage is flatulence. However, no current limit is known to date. Even in a study in which the test persons took a daily dose of 90 milligrams over a longer period of time, no obvious side effects occurred.

What is the difference between sulforaphane and DIM?

DIM stands for di-indolyl methane, which is also a secondary plant substance. It is mainly found in cruciferous vegetables. Thus, both substances can be found in various types of cabbage, for example.

Both substances are secondary plant substances.

Both substances have an anticarcinogenic effect and can thus contribute to inhibiting the development of cancer. DIM particularly inhibits the conversion of oestrone into its carcinogenic metabolite.

Thus, DIM inhibits the development of some types of cancer, including breast, colon and prostate cancer. (8)

Decision: What types of sulforaphane are there and which is right for you?

Sulforaphane is largely offered in two different forms. You can choose between

  • Powder
  • Capsules

different types. In the next few lines we will show you the advantages and disadvantages of these two forms.

What distinguishes sulforaphane powder and what are its advantages and disadvantages?

Like every form of administration, sulforaphane powder also has certain advantages and disadvantages. For example, sulforaphane in powder form is absorbed more quickly by the body and can also be adapted to individual needs without any problems.

Advantages
  • Doseable
  • Fast absorption
  • Somewhat cheaper
Disadvantages
  • Overview of quantity
  • More time-consuming to take
  • Difficult to combine with other things

When you have a powder in front of you, it can easily happen that you miss the end of the quantity. Taking it is also a bit more time-consuming, as the amount first has to be weighed and then absorbed.

What are the advantages and disadvantages of sulforaphane capsules?

If you are on the road a lot, then capsules have clear advantages. They can be taken along without any problems and can also be combined with other active ingredients without any problems.

Advantages
  • Easy transport
  • Take several active ingredients at the same time
  • Delayed release
Disadvantages
  • Only certain quantities
  • Problems swallowing
  • Possibly shorter shelf life

If you have problems swallowing tablets, this can of course be a criterion for exclusion. Likewise, you can only swallow a certain amount at a time (the unit of the tablet). So everyone has to decide for themselves.

Buying criteria: You can compare and evaluate sulforaphane based on these factors

Dosage

When it comes to dosage, it is important to distinguish between the intended use. If sulforaphane is to be taken for preventive purposes, a dose of between 5 and 15 milligrams is recommended.

If taken as part of a therapy, the dosage should be doubled to at least 30 milligrams. This amount can even be increased to much more, for example, patients were treated with as much as 90 milligrams at the Heidelberg University Hospital.

Dosage form

Many people take sulforaphane naturally, by eating cruciferous vegetables. Broccoli or specially cultivated broccoli with an increased concentration of sulforaphane are used particularly frequently.

For therapeutic use, capsules or powder can also be used, as it is otherwise very difficult to obtain the necessary amount. The intake can be well controlled via the products.

Additional ingredients

Sulforaphane is mostly offered in its pure form in capsules or powder. However, it can easily be combined with other active ingredients and natural things. For example, the active ingredients sulforaphane and sorafenib are a good combination that strengthens each other. (9)

However, it should not be combined with agents that promote exactly the opposite and contain substances such as prooxdians that stimulate oxidation.

Facts worth knowing about sulforaphane

How, when and for how long is it best to take sulforaphane?

If the sulforaphane is to be ingested via broccoli or other vegetables, these should be as fresh as possible and only steamed briefly. This preserves the highest concentration.

An alternative are broccoli sprouts, which have a high concentration of sulforaphane.

If you take capsules or powder, make sure you take them at regular intervals and combine them with other foods. The duration can be chosen personally.

What is the shelf life of sulforaphane preparations?

As a rule, these preparations have a certain shelf life, similar to other preparations. Sulforaphane preparations can therefore be stored very well and can also be bought in stock without any problems.

The preparations should be kept in a cool and light-protected place and can then be stored in this place for a longer period of time. There are no special requirements to be observed.

Which foods contain sulforaphane?

As already mentioned, a lot of sulforaphane can be found in broccoli, Brussels sprouts and cauliflower. In general, a standard broccoli of 500 to 700 grams contains about 30 to 50 mg sulforaphane. Broccoli sprouts have the absolute super content of sulforaphane - they are said to contain 10 to 100 times as much sulforaphane as "adult" broccoli.

Alternative foods are cabbage, kohlrabi, radishes, cresses, rocket, rapeseed and turnips. These foods also contain a certain amount of sulforaphane.

Can I give sulforaphane to my child?

The active ingredient sulforaphane can be given to children in an adapted dosage. The effects mentioned above can also occur in children and have a positive effect. Thus, various diseases can be influenced to a certain extent with this active ingredient.
For example, a study has shown that the intake of sulforaphane has a positive effect on the development of autism. Social behaviour is demonstrably influenced by the intake. (10)

Can I give sulforaphane to my dog?

Sulforaphane can also be mixed into dog food without any problems. At the moment, there are no studies on the verifiable effect of sulforaphane. However, some dog owners report about their positive experiences.

That this active ingredient strengthens the immune system, similar to humans, or also supports cancer therapy. Sulforaphane can be helpful for a variety of different complaints, but it is best to consult a veterinarian.

Image source: Sanchort/ 123rf.com

References (10)

1. Ingrid Herr, Vanessa Rausch, Markus W. Büchler (2013)
Source

2. Fawzy Elbarbry, Nehad Elrody (2011)
Source

3. Marc A. Riedl, M.D., M.S., Andrew Saxon, M.D., and David Diaz-Sanchez, Ph.D... (2008) 10.1016/j.clim.2008.10.007
Source

4. University of East Anglia. (2010) ScienceDaily
Source

5. Koramit Suppipat, Chun Shik Park, Ye Shen, Xiao Zhu, and H. Daniel Lacorazza ... (2012) 10.1371/journal.pone.0051251
Source

6. Klinik St. Georg (2008)
Source

7. Nathan V. Matushesk, iElizabeth H. Jeffery (2001) https://doi.org/10.1021/jf010809a
Source

8. Prof. Dr. Ingrid Herr (2014)
Source

9. Rausch V1, Liu L, Kallifatidis G, Baumann B, Mattern J, Gladkich J, Wirth T, Schemmer P, Büchler MW, Zöller M, Salnikov AV ... (2010) doi: 10.1158/0008-5472.CAN-10-0066
Source

10. Kanwaljit Singh, Susan L. Connors, Eric A. Macklin, Kirby D. Smith, Jed W. Fahey, Paul Talalay, and Andrew W. Zimmerman ... (2014) https://doi.org/10.1073/pnas.1416940111
Source

Why you can trust me?

Senfölbombe der Kreuzblütler – pflanzlicher Verteidigungsmechanismus mit therapeutischer Wirkung
Ingrid Herr, Vanessa Rausch, Markus W. Büchler (2013)
Go to source
Potential health benefits of sulforaphane: A review of the experimental, clinical and epidemiological evidences and underlying mechanisms
Fawzy Elbarbry, Nehad Elrody (2011)
Go to source
Oral Sulforaphane increases Phase II antioxidant enzymes in the human upper airway
Marc A. Riedl, M.D., M.S., Andrew Saxon, M.D., and David Diaz-Sanchez, Ph.D... (2008) 10.1016/j.clim.2008.10.007
Go to source
Eating broccoli could guard against arthritis
University of East Anglia. (2010) ScienceDaily
Go to source
Sulforaphane Induces Cell Cycle Arrest and Apoptosis in Acute Lymphoblastic Leukemia Cells
Koramit Suppipat, Chun Shik Park, Ye Shen, Xiao Zhu, and H. Daniel Lacorazza ... (2012) 10.1371/journal.pone.0051251
Go to source
Sekundäre Pflanzenstoffe aus Kreuzblütlern (Cruciferen) bei Krebs
Klinik St. Georg (2008)
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Comparison of the Bioactivity of Two Glucoraphanin Hydrolysis Products Found in Broccoli, Sulforaphane and Sulforaphane Nitrile
Nathan V. Matushesk, iElizabeth H. Jeffery (2001) https://doi.org/10.1021/jf010809a
Go to source
Der Krebs isst mit - Ernährung und Tumorchirugie
Prof. Dr. Ingrid Herr (2014)
Go to source
Synergistic activity of sorafenib and sulforaphane abolishes pancreatic cancer stem cell characteristics.
Rausch V1, Liu L, Kallifatidis G, Baumann B, Mattern J, Gladkich J, Wirth T, Schemmer P, Büchler MW, Zöller M, Salnikov AV ... (2010) doi: 10.1158/0008-5472.CAN-10-0066
Go to source
Sulforaphane treatment of autism spectrum disorder (ASD)
Kanwaljit Singh, Susan L. Connors, Eric A. Macklin, Kirby D. Smith, Jed W. Fahey, Paul Talalay, and Andrew W. Zimmerman ... (2014) https://doi.org/10.1073/pnas.1416940111
Go to source
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